Developmental patterns of torsinA and torsinB expression
نویسندگان
چکیده
منابع مشابه
Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.
A three base-pair deletion in the widely expressed TOR1A gene causes the childhood onset, neurological disease of DYT1 dystonia. Mouse Tor1a gene knockout also specifically affects the developing nervous system. However, in both cases, the basis of neuronal tissue specificity is unknown. TorsinA is one of four predicted mammalian torsin ATPases associated with assorted cellular activities (AAA+...
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ژورنال
عنوان ژورنال: Brain Research
سال: 2006
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2005.12.087